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There have also been combined outcomes from trials with regard to the utility of TMB. To this point, no possible clinical trials experienced shown that array of ICI remedy determined by a higher TMB above lower TMB increases OS.1,10 Most reports have evaluated TMB in certain tumors kinds, Whilst KEYNOTE-158 evaluated TMB retrospectively in 10 disti
There have also been combined final results from trials regarding the utility of TMB. To this point, no prospective scientific trials had demonstrated that collection of ICI remedy according to a higher TMB above lower TMB enhances OS.one,10 Most research have evaluated TMB in specific tumors forms, whereas KEYNOTE-158 evaluated TMB retrospectively